Health valueThe official Journal of ISSPOR-The Professional Society for Health Economics and Outcomes Research has today announced the publication of a special theme part of research reports that offer crucial insights into the complex health economy of the Alzheimer’s disease and related dementia, and an ADRDD) and an ADRDDD research and an ADRDDD research, and an ADRDD) and Route Research and Route Research and Adrdd) Treatments. Guest editors for the theme section are Thomas Rapp, PhD, Université Paris Cité, Chair Agingup!, And Liraes, Paris, France and Pei-Jung Lin, PhD, Center for the Evaluation of Health and Risk in Health, Institute for Clinical Research and Health Policy, MAS. The series was published in the issue of April 2025 of Health value.
“As the aging population grows and new diagnostic and treatment options arise, understanding the complex economic implications of ADRD becomes increasingly critical“Rapp and Lin noted in their opening article.”Conventional methods are often limited in recording the entire spectrum of ADRD costs and health effects, which requires the approval of new frameworks, broader considerations of economic results and a relentless focus on health equipment. Collecting articles in this theme form provides insight into these critical areas, which offers a route map for future research and policy. “
The section with the theme presents 8 research papers in 3 groups:
Group 1: Raffinage -Frameworks for evaluating ADRD interventions
- “Ipecad modeling workshop 2023 Cross-comparison challenge on cost-effectiveness models in Alzheimer’s disease,” by R Handel, WL Haring, F Kamgar and colleagues
- “New iPecad Open-Source Model framework for the assessment of the health technology of the early disease treatment of Alzheimer’s: Development and Use Cases,” by R Handel, WL Herring, S Grimm and colleagues
Group 2: Broadening the lens: Measuring the wider economic impact of ADRD
- “Indirect costs of Alzheimer’s disease: unpaid loss of care and loss of productivity,” by J Fox, Es Mearns, J Li and colleagues
- “Cost effectiveness of a digital supported healthcare management program for care providers of people with dementia,” by M Pfaff, W Hoffmann, M Boekholt and colleagues
- “The surplus direct social costs of dementia-related neuropsychiatric symptoms: a regional cohort study beyond Silo
- “A new approach to assess the value of informal care in Alzheimer’s disease,” by a Cheneau and T Rapp
Group 3: Tackling healthary in ADRD Care Innovations
- “Changes in spending outside the bag of drug spending on Medicare-beneficiaries with dementia under the inflation reduction Act: a simulation testing,” by Y Zhu, n Olhanski, KM Freund, JT Cohen, PJ Neumann and PJ Lin
- “Age and gender differences in the relationship between chronic pain and dementia in older Australians,” by r Haque, K Alam, J Gow, C Neville and Sa Keramat
The collection of articles in this theme form, highlights challenges and opportunities in the ADRD health economy. There will be various priorities in the future: standardizing economic evaluation methods, developing more extensive approaches to measuring economic impact and guaranteeing fair access to care innovations.
“With the aging of the population, these priorities become essential to guarantee the sustainability of future health care for the elderly that are affected by ADRD“Note the editors.”Since various innovations (pharmaceutical treatments for early stages of Alzheimer’s disease, diagnostic tools that use artificial intelligence -algorithms, etc.) indeed arrive at the health care markets, the need for a more accurate estimate of the associated potential benefits of crucial importance. We hope that this theme of further investigation, dialogue and policy development catalyzes to improve the lives of people affected by ADRD and their families. “